Clinical Trial Solutions

Interactive Response Technology (IRT)

Calyx’s extensive experience and award-winning IRT system optimizes randomization and clinical trial supply management (RTSM) processes to propel your development program forward.

Clinical Trial Solutions

Interactive Response Technology (IRT)

Calyx’s extensive experience and award-winning IRT system optimizes randomization and clinical trial supply management (RTSM) processes to propel your development program forward.

Right treatment. Right patient. Right time.

Calyx IRT is a robust Randomization and Trial Supply Management (RTSM) solution, proven across 4,500+ studies to reduce risks and optimize suppliesensuring trial sponsors and CROs meet key milestones through reliable, and flexible, on-time medication delivery.

Gain access to some of the industry’s most experienced IRT professionals and a solution that has evolved over nearly 30 years to meet the continuous challenges facing the pharmaceutical industry.

Calyx IRT. A solution you can trust. Every time.

 

Right treatment. Right patient. Right time.

Calyx IRT is a robust Randomization and Trial Supply Management (RTSM) solution, proven across 4,500+ studies to reduce risks and optimize suppliesensuring trial sponsors and CROs meet key milestones through reliable, and flexible, on-time medication delivery.

Gain access to some of the industry’s most experienced IRT professionals and a solution that has evolved over nearly 30 years to meet the continuous challenges facing the pharmaceutical industry.

Calyx IRT. A solution you can trust. Every time.

Improve data quality with proven IRT.

Calyx IRT system guides sites on how and when to enter patient data in alignment with the protocol and minimizes data errors through real-time data entry validation. Accurate questions and quality translations reduce ambiguity during data capture and Calyx’s flexible integrations reduce the need for data duplication.

irt system benefits section

Improve data quality with proven IRT.

irt system benefits section

Calyx IRT system guides sites on how and when to enter patient data in alignment with the protocol and minimizes data errors through real-time data entry validation. Accurate questions and quality translations reduce ambiguity during data capture and Calyx’s flexible integrations reduce the need for data duplication.

Simplifying the complex

Built on decades of experience and designed by the most experienced project teams in the industry, Calyx IRT simplifies the complications involved with RTSM. From simple blocked and stratified designs to more complex adaptive trial designs, Calyx IRT delivers advanced randomization and trial management suitable for all trials.

Adaptable functionality

A 4,500+ trial-tested system, Calyx IRT uses automated workflows, self-service tools, and reporting to meet the unique needs of each trial and each system user. Take advantage of flexible, robust medication management algorithms, simplified study and site management, and protocol-tailored patient management with Calyx IRT.

Accelerated study start-up

Need to start a trial quickly? By taking advantage of pre-defined standards, Calyx can deliver a reliable IRT system for User Acceptance Testing only 4 weeks after specification sign-off. Calyx’s experienced team will recommend the optimal IRT design for you based on their wealth of experience building and supporting trials.

Increased Protocol Compliance

What you care about is the quality of your data. Calyx IRT is configured to match protocol requirements and reduce the risk of unblinding, randomization imbalance, or mis-dispensing, resulting in increased protocol compliance and high data quality.

Simplifying the complex

Built on decades of experience and designed by the most experienced project teams in the industry, Calyx IRT simplifies the complications involved with RTSM. From simple blocked and stratified designs to more complex adaptive trial designs, Calyx IRT delivers advanced randomization and trial management suitable for all trials.

Adaptable functionality

A 4,500+ trial-tested system, Calyx IRT uses automated workflows, self-service tools, and reporting to meet the unique needs of each trial and each system user. Take advantage of flexible, robust medication management algorithms, simplified study and site management, and protocol-tailored patient management with Calyx IRT.

Accelerated study start-up

Need to start a trial quickly? By taking advantage of pre-defined standards, Calyx can deliver a reliable IRT system for User Acceptance Testing only 4 weeks after specification sign-off. Calyx’s experienced team will recommend the optimal IRT design for you based on their wealth of experience building and supporting trials.

Increased Protocol Compliance

What you care about is the quality of your data. Calyx IRT is configured to match protocol requirements and reduce the risk of unblinding, randomization imbalance, or mis-dispensing, resulting in increased protocol compliance and high data quality.

Effective RTSM, backed by proven experience.

Getting randomization right and getting supplies to sites on-time can be a risky business. Trust Calyx IRT – and the decades of experience behind it – to reduce RTSM risks and help your trial succeed.

4.5K+
TRIALS
2.6M+
PATIENTS
500
APPROVALS
SUPPORTED
250+
ADAPTIVE
TRIALS
4.5K+
TRIALS
2.6M+
PATIENTS
500
APPROVALS
SUPPORTED
250+
ADAPTIVE
TRIALS

Expertise matters.

Successfully used in over 4,500 studies and having supported over 500 regulatory approvals to date, Calyx is proven to deliver reliable and effective RTSM. For all therapeutic areas. For all phases. For all trial designs.

Calyx IRT experience over the past 5 years

Experience by Therapeutic Areas
irt system expereience by therapeautic areas graph
irt system aligning point

Platform trials? Sure, we can adapt.

An effective IRT system – and the expertise of the provider who delivers it – are indispensable in controlling randomization and supply risks in adaptive and platform trials. The system should be highly configurable and the IRT team should have the experience needed to foresee the types of adaptations that will likely arise.

Calyx IRT has been used in over 250 adaptive trials to date, delivering comprehensive processes and technology proven to adapt to requirements that are not planned up front, driving the success of adaptive and platform trials.

irt system aligning point

The need for speed.

The criticality of the COVID-19 pandemic saw the emergence of fast-paced study start-ups, with the goal to get treatments approved as quickly as possible. And Calyx delivered.

During the pandemic, Calyx IRT supported over 25 studies of COVID treatments and vaccines, half of which required accelerated timelines. Calyx responded, delivering reliable IRT systems in as little as 6 days. This was accomplished through efficient technology, the use of core standards, and the expertise of Calyx IRT solution consultants, who leveraged their experience for fast decisions, achieving more in less time.

irt system aligning point

Supporting the unexpected.

When unexpected challenges arise mid-trial, you need confidence in the support your IRT partner can provide.

At the beginning of 2020, Calyx IRT was supporting over 750 live trials. Each one was impacted by site and depot closures during the COVID-19 pandemic.

Calyx IRT consultants drew from their expertise to implement the right RTSM solution for each trial. By anticipating depot closures and shipping more medication to sites ahead of time, transferring patients to different sites if their site was closed, and shipping medication directly to patients if they were unable to leave their homes, Calyx IRT enabled each patient in each trial to receive their medication, freeing up study managers to focus on other challenges.

irt system aligning point

Reduce drug waste. Save trial costs.

A large proportion of clinical trial costs are attributable to the production and management of medication. Calyx IRT can help to minimize these costs by reducing the amount of drug wasted during clinical trials.

By automating trial supply chains with Calyx’s advanced IRT inventory management settings, available medication is directed to actively recruiting sites, ensuring they have sufficient stock to supply their patients, while limiting the quantity of medication wasted by overstocking unproductive sites.

Seamless integrations.

By integrating Calyx IRT with other eClinical systems, sponsors boost productivity and improve data quality, reducing the need for data duplication and reconciliation at the end of the trial.

Calyx’s experience in integrating IRT with other eClinical systems is second to none, whether they are simple IRT-to-EDC integrations or more complex, blinded central lab integrations and electronic patient reported outcome (ePRO) scoring.

irt seamless integrations

Seamless integrations.

irt seamless integrations

By integrating Calyx IRT with other eClinical systems, sponsors boost productivity and improve data quality, reducing the need for data duplication and reconciliation at the end of the trial.

Calyx’s experience in integrating IRT with other eClinical systems is second to none, whether they are simple IRT-to-EDC integrations or more complex, blinded central lab integrations and electronic patient reported outcome (ePRO) scoring.

IRT System Consulting

Calyx IRT experts bring a collective 100 years’ experience in applying advanced technology to optimize RTSM, enabling Calyx customers to run effective and efficient clinical trials.

Whether your trial is simple or complex, local or global, with 50 patients or 5,000, gain access to some of the industry’s most experienced IRT professionals to help you get the most out of your IRT system and drive your trials’ success.

IRT System Consulting

Calyx IRT experts bring a collective 100 years’ experience in applying advanced technology to optimize RTSM, enabling Calyx customers to run effective and efficient clinical trials.

Whether your trial is simple or complex, local or global, with 50 patients or 5,000, gain access to some of the industry’s most experienced IRT professionals to help you get the most out of your IRT system and drive your trials’ success.

Library

Increase Efficiencies through Effective IRT Partnering

How can a program management approach combined with IRT standards overcome obstacles, alleviate RTSM-related pressures, and allow study teams to focus on other clinical development needs? Read the Case Study.
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Reducing Drug Waste in a Complicated Protocol: Calyx IRT

Learn how sponsors reduced buffer stock by 60% while using advanced inventory management settings in Calyx IRT.
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Ultimate Guide: IRT approaches to help with reducing drug waste

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Discover the Calyx Difference with Calyx IRT

Gain confidence in RTSM through Calyx IRT, an extremely robust system built on decades of experience and delivered by the most experienced project teams in the industry.
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